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To understand how Viagra works we need to understand how an erection comes about. Nitric Oxide (NO) is released with sexual stimulation from nerve endings and endothelial cells in the corpus cavernosum of the penis. An enzyme then converts guanosine triphosphate (GTP) into cyclic guanosine monophosphate (cGMP). cGMP causes the smooth muscle of the penis to relax, which causes an inflow of blood which then leads to an erection. cGMP is then hydrolysed back to the inactive GMP by phosphodiesteras type 5 (PDE5). Men who suffer from erectile dysfunction often produce too little amounts of NO. This means that the small amount of cGMP they produce is broken down at the same rate and therefore doesn039;t have the time to accumulate and cause a prolonged vasodilation effect. Sildenafil (Viagra) works by inhibiting the enzyme Buy viagra without seeing doctor.

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The drugās label also warns of erections lasting longer than four hours, painful erections lasting longer than six hours, headache, flushed skin and vision problems. Pfizer Inc. said in its most recent quarterly filing with the Securities and Exchange Commission that sales of the drug rose 5 percent ā to 438 million in the first quarter of the year.

Viagra could cause blindness in men with eye problems, and even those with seemingly normal vision, a new study has found. Australian researchers say an ingredient in anti-impotence drugs may permanently affect the vision of men with an inherited eye condition. It could also affect those with normal sight who carry one gene which is linked with developing eye problems. Scroll down for video.

Hence the drug is known to be effective in treating pulmonary hypertension also.]